| Item Type | Name |
|
Concept
|
Cognitive Dysfunction
|
|
Academic Article
|
Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
|
|
Academic Article
|
Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
|
|
Academic Article
|
Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.
|
|
Academic Article
|
Obesity-induced cognitive impairment in older adults: a microvascular perspective.
|
|
Academic Article
|
Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
|
|
Academic Article
|
Age-related decline in peripheral vascular health predicts cognitive impairment.
|
|
Academic Article
|
Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
|
|
Academic Article
|
Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
|
|
Academic Article
|
Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
|
|
Academic Article
|
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
|
|
Academic Article
|
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
|
|
Academic Article
|
Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
|
|
Academic Article
|
Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults.
|
|
Academic Article
|
Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
|
|
Academic Article
|
Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.
|
|
Academic Article
|
Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
|
|
Academic Article
|
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
|
|
Academic Article
|
Assessment of endothelial function in leptomeningeal arterioles derived from patients with Alzheimer's disease and vascular cognitive impairment.
|
|
Academic Article
|
Single Mild Traumatic Brain Injury Induces Persistent Disruption of the Blood-Brain Barrier, Neuroinflammation and Cognitive Decline in Hypertensive Rats.
|
|
Academic Article
|
CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
|
|
Academic Article
|
Traumatic brain injury-induced cerebral microbleeds in the elderly.
|
|
Academic Article
|
Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis.
|
|
Academic Article
|
Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
|
|
Academic Article
|
Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.
|
|
Academic Article
|
Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
|
|
Academic Article
|
Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
|
|
Academic Article
|
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
|
|
Academic Article
|
Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
|
|
Academic Article
|
Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice.
|
|
Grant
|
Age-related vascular cognitive impairment: role of endothelial senescence
|
|
Grant
|
Cerebral microhemorrhages and gait dysfunction in aging
|
|
Grant
|
Radiation-induced astrocyte dysfunction and cognitive decline
|
|
Academic Article
|
Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis.
|
|
Grant
|
Cerebromicrovascular rejuvenation by heterochronic blood exchange
|
|
Academic Article
|
Hypertension-induced cognitive impairment: from pathophysiology to public health.
|
|
Academic Article
|
Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
|
|
Academic Article
|
Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
|